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October 11, 2025Tropical Journal of Pharmaceutical ResearchOpen Access

Characterization of in vitro spray-dried self-nanoemulsifying drug delivery systems for oral delivery of Bundung extract

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Authors

NNNoval NovalSASaftia AryzkiKNKunti Nastiti

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Overview

Observational analysis demonstrated enhanced solubility and bioavailability of Bundung extract using self-nanoemulsifying drug delivery systems.

Key Points

  • Formulation 1 of L-SNEDDS achieved 99.3% transmittance and had the smallest droplet size, indicating excellent emulsification.
  • Formulation 1 also showed the highest antioxidant activity, making it a promising option for oral delivery of Bundung extract.
  • Using a spray drying technique, formulation 3 converted liquid SNEDDS to solid SNEDDS with a 100% yield, optimizing drug delivery.
  • Characterization tests including droplet size, polydispersity index, and zeta potential confirmed that formulations 1, 2, 3, and 5 met the required standards.

Cite This Study

Noval et al. (2025) studied this question.

synapsesocial.com/papers/68e9b1b5ba7d64b6fc131e7bhttps://doi.org/10.4314/tjpr.v24i4.1
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