Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
September 5, 2025Oriental Journal Of ChemistryOpen Access

Comparative Study of Snedds and Sedds for Enhancing Oral Delivery of Vildagliptin

View Full Paper
Ask AI
Bookmark
Share

Authors

RSR. V. SinghRTRajkumari Thagale

Discussion

Loading...

Member takes

Overview

Comparative study highlights enhanced bioavailability of vildagliptin using SNEDDS over SEDDS, suggesting improved drug delivery strategies.

Key Points

  • SNEDDS significantly improved oral bioavailability of vildagliptin compared to SEDDS, showing enhanced stability.
  • In vitro analyses demonstrated improved dissolution rates and drug release patterns for SNEDDS, underscoring its effectiveness.
  • The study assessed formulation stability, droplet size, and zeta potential to ensure optimized delivery systems.
  • Despite advancements, commercial application faces challenges regarding formulation scalability and regulatory compliance.

Cite This Study

Singh et al. (2025) studied this question.

synapsesocial.com/papers/68c23a2cb210217d6477fa3dhttps://doi.org/10.13005/ojc/410440
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Advances in Self-Nanoemulsifying Drug Delivery Systems: Mechanistic Insights and Formulation Strategies2025
  2. 2Revolutionizing Drug Delivery: The Promise of Self-emulsifying Systems in Overcoming Bioavailability Challenges2025
  3. 3Advancements and Innovations in Herbal and non-herbal, Self-Micro emulsifying Drug Delivery Systems (SMEDDS): A Comprehensive Review2025
  4. 4QbD‐Based Development of Self‐Nanoemulsifying Drug Delivery System for Codelivery of Simvastatin and Ezetimibe With Enhanced In Vitro Dissolution2025
  5. 5Pluronic F-68 Triblock Copolymer Architecture for a Next-Generation Self-Nanoemulsifying System: Overcoming Drug Trapping and Dosage Challenges of Candesartan Cilexetil2025