October 10, 2025Indian Journal of Veterinary PathologyOpen Access

A widely metastatic hepatocellular carcinoma and intrahepatic bile duct cystadenocarcinoma in Spitz dog

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Authors

RMR. MadheswaranTamil Nadu Veterinary and Animal Sciences University

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Implication

Post mortem analysis reveals metastatic hepatocellular carcinoma and intrahepatic bile duct cystadenocarcinoma in a 10-year-old Spitz dog, suggesting severe systemic involvement.

Key Points

Malignant tumors identified include hepatocellular carcinoma and intrahepatic bile duct cystadenocarcinoma.
Multiple metastatic growths were found in the lungs, lymph nodes, and other organs during necropsy.
Tumor nodules displayed pleomorphic neoplastic cells with significant nuclear abnormalities and mitotic activity.
Immunohistochemical analysis indicated varied expression levels of specific markers in neoplastic and normal cells.

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R. Madheswaran (2025) studied this question.

synapsesocial.com/papers/68e861a57ef2f04ca37e4811 https://doi.org/10.56093/djdznb79

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Implication

Post mortem analysis reveals metastatic hepatocellular carcinoma and intrahepatic bile duct cystadenocarcinoma in a 10-year-old Spitz dog, suggesting severe systemic involvement.

A widely metastatic hepatocellular carcinoma and intrahepatic bile duct cystadenocarcinoma in Spitz dog

Discussion

Member takes

Implication

Key Points

Cite This Study

A widely metastatic hepatocellular carcinoma and intrahepatic bile duct cystadenocarcinoma in Spitz dog

Discussion

Member takes

Implication

Key Points

Cite This Study

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