Pathological and immunohistochemical characterization of ovarian papillary adenocarcinoma in a spitz dog

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Case report details immunohistochemical features and tumor characteristics in a spitz dog, indicating malignancy.

Ovarian papillary adenocarcinoma was identified in a 12-year-old spitz dog presenting with abdominal distension.
Histopathological analysis revealed a papillary tumor structure with cellular atypia and irregular branching.
Immunohistochemistry showed strong expression of pan-cytokeratin and estrogen receptor, confirming the tumor type.
Surgical removal of the mass was performed using ovariohysterectomy, indicating an interventional approach.

M. Sasikala (2025) studied this question.

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