September 14, 2025

Grossly normal-appearing livers have low risk of metastatic malignancy in dogs with splenic masses.

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Discussion

Retrospective review found low risk of hepatic malignancy in dogs with normal liver appearance, suggesting clinical implications.

Dogs with grossly normal-appearing livers showed a low risk of hepatic malignancy, emphasizing the importance of liver appearance.
Out of 273 dogs with splenic masses, 38% were diagnosed with splenic malignancy, predominantly hemangiosarcoma.
Statistical correlation indicated that liver abnormalities are significantly linked to metastatic disease originating from splenic tumors.
A predictive linear regression formula could help assess the likelihood of malignancy based on liver appearance.

Soula et al. (2025) studied this question.

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