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September 23, 2025Anatolian Current Medical JournalOpen Access

Receptor gene expressions and their association with biochemical parameters in primary hyperparathyroidism patients

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Authors

ÖAÖzge Karabıyık Acar

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Overview

Analysis reveals distinct gene expression correlations with biochemical markers in PHPT patients.

Key Points

  • Analysis found notable correlations between gene expression levels and serum calcium in PHPT patients.
  • Lower expression of calcium-sensing receptor was identified in small adenomas among the subjects.
  • RNA was isolated from parathyroid adenoma samples using one-step reverse transcription quantitative PCR.
  • This research highlights the importance of understanding receptor gene expression in managing primary hyperparathyroidism.

Cite This Study

Özge Karabıyık Acar (2025) studied this question.

synapsesocial.com/papers/68d4419f713b0b5dfea805bbhttps://doi.org/10.38053/acmj.1752081
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Immunohistochemical Expression of CaSR, VDR, and AMA in Parathyroid Tumors Linked to Hypercalcemia Severity in Primary Hyperparathyroidism2025
  2. 2Temporal Variation of Biochemical Markers and Adenoma Predictors in Normocalcemic Primary Hyperparathyroidism: A Multicenter Retrospective Analysis2025
  3. 3Role of vitamin D receptor and calcium sensing receptor in parathyroid cancer2026
  4. 4Can vitamin D supplementation be dangerous? 25-Hydroxyvitamin D and 1,25-hydroxyvitamin D concentration in healthy population and primary hyperparathyroidism: a single-center experience and literature review2025
  5. 5Clinical, biochemical, and radiological profile of adult patients with primary hyperparathyroidism operated at a single tertiary care center in North India2025