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September 16, 2025

Omics-Assisted Biomarkers Identification and Docking-Based Therapeutic Exploration of Moringa Phytoconstituents in Chronic Obstructive Pulmonary Disease

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Authors

BVBasavaraj VastradSPShivaling PattanashettiCVChanabasayya Vastrad

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Overview

Bioinformatics reveals potential biomarkers and therapeutic targets in chronic obstructive pulmonary disease, indicating new avenues for treatment.

Key Points

  • A total of 956 differentially expressed genes were identified in COPD, revealing genetic targets for diagnosis and therapy.
  • The analysis outlined gene ontology terms and pathways highlighting immune response and cellular stimuli in COPD progression.
  • Next generation sequencing combined with bioinformatics enabled discovery of key miRNAs and therapeutic drugs for COPD management.
  • Phytoconstituents from Moringa were screened as potential inhibitors, suggesting alternative therapeutic avenues for COPD patients.

Cite This Study

Vastrad et al. (2025) studied this question.

synapsesocial.com/papers/68d43c79713b0b5dfea7bc58https://doi.org/10.21203/rs.3.rs-7522725/v1
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