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September 20, 2025Narra XOpen Access

Phytochemical screening of bioactive compounds and antioxidant activity of methanol extract from Melia Azedarach L. fruit: Exploring for antidiabetic potential

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Authors

QAQurratu AiniNNNurdin NurdinMMMustanir Mustanir

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Overview

This analysis reveals antioxidant activity and bioactive compounds in Melia azedarach, suggesting antidiabetic potential through various interactions.

Key Points

  • Moderate antioxidant activity was observed with IC50 = 102.27 µg/mL, showcasing the extract's potential health benefits.
  • M. azedarach fruit contains high total phenolic content (479.8 mg GAE/g) and total flavonoid content (52.7 mg QE/g).
  • Molecular docking analysis indicated strong binding affinities for multiple targets, showing potential for antidiabetic compounds.
  • Phytochemical screening revealed diverse constituents including terpenoids, flavonoids, and phenolics that may support glucose regulation.

Cite This Study

Aini et al. (2025) studied this question.

synapsesocial.com/papers/68d43a00713b0b5dfea79f64https://doi.org/10.52225/narrax.v3i2.229
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