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August 18, 2025Chemistry & Biodiversity

Effects of Selected Medicinal Plants on Enzymatic Targets Related to Diabetes Mellitus and Obesity

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Authors

TGTuğba GünbatanSPSultan PekacarBÖBurçin Özüpek

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Overview

In vitro analysis demonstrates selected medicinal plants inhibit enzymes related to diabetes and obesity, suggesting potential therapies.

Key Points

  • Alhagi maurorum exhibited strong inhibitory activity against α-glucosidase, with an IC50 value of 45.16 µg/mL, highlighting its potential in diabetes treatment.
  • Crocus ancyrensis and Scabiosa rotata showed moderate α-amylase inhibition, with activities of 38.54% and 28.79%, respectively, indicating promising candidates for further study.
  • High levels of phenolics and flavonoids in Tilia tomentosa, Thymus praecox, and Berberis crataegina contributed to notable antioxidant activities, enhancing their therapeutic prospects.
  • Activity-guided fractionation of A. maurorum extract may lead to the discovery of new compounds with antidiabetic properties, emphasizing the need for further exploration.

Cite This Study

Günbatan et al. (2025) studied this question.

synapsesocial.com/papers/68af2d89cf1dd9ea359e5eebhttps://doi.org/10.1002/cbdv.202500868
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