Cardiac light chain amyloidosis secondary to Waldenström's macroglobulinemia: A case report and review

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Diagnosis of cardiac amyloidosis secondary to Waldenström's macroglobulinemia is complex and often delayed.
The patient exhibited heart failure symptoms, confirmed via echocardiography and Congo red staining, indicating cardiac dysfunction.
Chemotherapy regimens (BR and BRD) provided only a partial response, highlighting the need for personalized treatment strategies.
Improved clinical detection and tailored therapies are essential due to the rarity and severity of the condition.

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Case report highlights challenges of diagnosing cardiac amyloidosis and Waldenström's, suggesting improved vigilance in clinical practice.

Du et al. (2025) studied this question.

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Case report highlights challenges of diagnosing cardiac amyloidosis and Waldenström's, suggesting improved vigilance in clinical practice.