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September 10, 2025Current Cardiology Reviews

Cardiac Repair and Mesenchymal Stem Cells: Exploring New Frontiers in Regenerative Medicine

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Authors

SNSadia NazirTMTahir MaqboolSSSümeyra Savaş

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Overview

This review explores MSC therapies for cardiac repair post-myocardial infarction, highlighting challenges and outcomes.

Key Points

  • MSCs show potential for cardiac repair by differentiating into cardiomyocytes and enhancing angiogenesis.
  • Clinical trials exhibit variable results in cardiac function improvements post-MI, indicating challenges in therapy application.
  • Preclinical studies demonstrate MSCs' roles in modulating immune responses and reducing fibrosis for tissue remodeling.
  • Further research is essential to harness the full regenerative potential of MSCs in cardiac repair settings.

Cite This Study

Nazir et al. (2025) studied this question.

synapsesocial.com/papers/68c24126b210217d6479dd4ahttps://doi.org/10.2174/011573403x376065250728094646
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Current perspectives on regenerative potential of mesenchymal stem cells in alleviating cardiac injuries: Molecular pathways and therapeutic enhancement2025 · 3 citations
  2. 2Regenerative strategies for myocardial infarction: Integrating cell therapy and scaffold design2025
  3. 3Stem cell therapy for cardiovascular diseases: Mechanisms, challenges, and therapeutic prospects2025
  4. 4Stem Cell Therapy for Myocardial Infarction and Heart Failure: A Comprehensive Systematic Review and Critical Analysis2025
  5. 5Multifaceted mechanisms and targeted delivery of mesenchymal stem cell-derived exosomes in cardiovascular diseases: a translational medicine perspective2025 · 1 citations