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August 20, 2025World Journal of Stem Cells

Current perspectives on regenerative potential of mesenchymal stem cells in alleviating cardiac injuries: Molecular pathways and therapeutic enhancement

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Authors

ASAsmaa Mohammed ShamsEldeenSHSara Adel HosnyKMKhaled Maghib

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Overview

Review reveals how mesenchymal stem cells and their extracellular vesicles improve cardiac injuries, highlighting challenges in homing and therapeutic strategies.

Key Points

  • Mesenchymal stem cells effectively treat cardiac injuries, enhancing recovery through regenerative mechanisms.
  • Numerous clinical studies indicate that MSC therapy leads to improved cardiac function, yet obstacles remain.
  • This review examines cellular pathways involving MSCs and their extracellular vesicles in cardiac repair strategies.
  • Understanding MSC homing challenges may enable better therapeutic applications in regenerative medicine.

Cite This Study

ShamsEldeen et al. (2025) studied this question.

synapsesocial.com/papers/68af3e34cf1dd9ea359ea9d7https://doi.org/10.4252/wjsc.v17.i8.107480
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