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September 10, 2025Journal of Global HealthOpen Access

Association between estimated glucose disposal rate and cardiovascular disease prevalence and mortality outcomes in metabolic dysfunction-associated steatotic liver disease: a comparative analysis of insulin resistance markers

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Authors

XCXiaoli ChenLDLeilei DuJPJia Peng

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Overview

Observational analysis links estimated glucose disposal rate with cardiovascular outcomes in MASLD, suggesting its predictive value over traditional markers.

Key Points

  • Lower estimated glucose disposal rate levels are linked to higher risks of cardiovascular disease and mortality.
  • Logistic regression revealed statistically significant associations with cardiovascular disease prevalence and mortality outcomes.
  • The observational study employed survey-weighted logistic regression and Cox proportional hazards models on NHANES data.
  • Incorporating estimated glucose disposal rate enhances predictive models for cardiovascular disease risk and mortality.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c24126b210217d6479da73https://doi.org/10.7189/jogh.15.04249
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Estimated glucose disposal rate and its dual role in hyperlipidemia risk and mortality: a secondary analysis of retrospective cohort data from U.S. and Chinese2025
  2. 2Estimated Glucose Disposal Rate and Mortality in Cardiovascular Kidney Metabolic Syndrome: Nonlinear Associations and Stratified Prognostic Significance by Glycometabolic Phenotypes2025
  3. 3Linking Estimated Glucose Disposal Rate to Major Adverse Cardio-Cerebrovascular Events in Populations With and Without Diabetes: A Systematic Review and Meta-Analysis2025
  4. 4Association between metabolic dysfunction-associated steatotic liver disease and insulin resistance in individuals with normoglycemia2025 · 6 citations
  5. 5The association between insulin resistance assessed by estimated glucose disposal rate and stroke prevalence and mortality in non-diabetic people: evidence from two prospective cohorts2025