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September 10, 2025Biomedicine HubOpen Access

Effect of Adults and Pediatric-inspired Schemes on Negative Measurable Residual Disease and Overall Survival in Adults with Acute Lymphoblastic Leukemia: A Retrospective Analysis from the Hematology Department at Hospital Regional de Alta Especialidad de Ixtapaluca, Mexico

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Authors

CPChristian Omar Ramos PeñafielIOIrma Olarte‐CarrilloAGAdán Germán Gallardo-Rodríguez

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Overview

Retrospective analysis of treatment outcomes in adults with acute lymphoblastic leukemia, highlighting disparities in survival rates and disease remission in pediatric and adult schemes.

Key Points

  • Patients using pediatric-inspired treatment schemes experienced significantly higher overall survival rates.
  • The study found complete remission rates of 67.4% in pediatric scheme patients compared to 57.3% in adult scheme recipients.
  • This analysis included clinical records of 460 patients treated for acute lymphoblastic leukemia between 2018 and 2023.
  • Strict screening for measurable residual disease significantly impacts prognosis for adult acute lymphoblastic leukemia patients.

Cite This Study

Peñafiel et al. (2025) studied this question.

synapsesocial.com/papers/68c2409bb210217d6479b3dahttps://doi.org/10.1159/000545952
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  4. 4Improved outcomes in elderly patients with acute lymphoblastic leukaemia using a paediatric‐based protocol—A prospective study2025
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