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September 10, 2025Zahedan Journal of Research in Medical SciencesOpen Access

The Impact of Aerobic vs. Resistance Exercises on Serum miR-204, miR-181, Metabolic Biomarkers and Physical Fitness in Diabetic Children: A Randomized Control Trial

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Authors

MSMesbah ShamsVMVazgen MinasianMHMahin Hashemipour

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Overview

Randomized controlled trial shows improved metabolic biomarkers and fitness in children with type 1 diabetes, indicating exercise effectiveness.

Key Points

  • Significant improvements in physical fitness were observed across both aerobic and resistance exercise groups.
  • Levels of fasting blood glucose and triglycerides notably decreased in both exercise groups compared to baseline values.
  • Real-time PCR was used to assess microRNA levels, but changes in miR-204 and miR-181 were insignificant.
  • Both exercise modalities proved effective in managing diabetes and enhancing cardiovascular fitness in participants.

Cite This Study

Shams et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d647985behttps://doi.org/10.5812/zjrms-163541
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Efficacy of Home-based Resistance Exercise and Game-based Exercise Training on microRNA-21-5p Expression and Non-Alcoholic Fatty Liver Biomarkers in Children with Type 1 Diabetes2025
  2. 2Effects of different types of exercise interventions on metabolic and cardiorespiratory fitness in children and adolescents with type 1 diabetes mellitus:a systematic review and network meta-analysis2025
  3. 3Comparative effects of aerobic exercise, resistance exercise and yoga on metabolic profile and cellular ageing in type 2 diabetes mellitus2025
  4. 4Effects of Different Exercise Interventions on Health Status in Overweight and Obese Children and Adolescents: A Network Meta-Analysis2025 · 3 citations
  5. 5Assessment of resistance and aerobic training with/ without Blood Flow Restriction and detraining period and their association with miR143/145 (rs4705342 and rs4705343) and IGF2BP2 (rs4402960 and rs1470579) gene polymorphisms in men with type 2 diabetes2025