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September 10, 2025Advanced Biomedical ResearchOpen Access

The Efficacy of Home-based Resistance Exercise and Game-based Exercise Training on microRNA-21-5p Expression and Non-Alcoholic Fatty Liver Biomarkers in Children with Type 1 Diabetes

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Authors

MYMuhammad YasirVMVazgen MinasianSHSilva Hovsepian

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Overview

Home-based resistance exercise and game-based training improve microRNA-21-5p and liver biomarkers in children with T1D, implying beneficial health effects.

Key Points

  • Increased microRNA-21-5p levels were observed in both exercise groups after the interventions, enhancing their potential as biomarkers.
  • Significant reductions were noted in liver enzymes alanine transaminase and aspartate aminotransferase, supporting improved liver function in participants.
  • Both exercise modalities showed positive effects on glycemic control, with reductions in HbA1c levels indicating better blood sugar management.
  • Cardiorespiratory fitness improved slightly post-intervention, while no significant differences were found between the two exercise groups.

Cite This Study

Yasir et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d64791dbehttps://doi.org/10.4103/abr.abr_105_24
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