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September 10, 2025Acta Biochimica Iranica

Assessment of resistance and aerobic training with/ without Blood Flow Restriction and detraining period and their association with miR143/145 (rs4705342 and rs4705343) and IGF2BP2 (rs4402960 and rs1470579) gene polymorphisms in men with type 2 diabetes

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Authors

HMHassan MoudiFFFoad FeizolahiARAlireza Rahimi

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Overview

Assessment highlights how blood flow restriction and genetic variations influence glycemic control in T2D patients.

Key Points

  • Resistance training with blood flow restriction showed improved glycemic control in men with type 2 diabetes, suggesting potential treatment benefits.
  • Genetic variations in miR-143/145 and IGF2BP2 polymorphisms significantly influenced the responses to training, indicating genetic factors in diabetes management.
  • Training sessions included both aerobic and resistance methods over 12 weeks, followed by a 6-week detraining period for comprehensive assessment.
  • Findings emphasize the importance of considering genetic polymorphisms along with exercise interventions in the management of type 2 diabetes.

Cite This Study

Moudi et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478d6e1https://doi.org/10.18502/abi.v3i2.19484
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Effect of Resistance and Aerobic Training with and Without Blood Flow Restriction and Detraining Period on Insulin Resistance in Men with Type 2 Diabetes: A Pilot Study2025
  2. 2The Impact of Aerobic vs. Resistance Exercises on Serum miR-204, miR-181, Metabolic Biomarkers and Physical Fitness in Diabetic Children: A Randomized Control Trial2025
  3. 3Effects of Blood Flow Restriction Training on Quadriceps Muscle Strength and Biochemical Parameters among Individuals with Type 2 Diabetes Mellitus: A Protocol for a Randomised Controlled Trial2025
  4. 4Implication of MATE2, OCT2 and ATM Genes Polymorphism and their Association with Metformin Efficacy and Glycemic Control in Type 2 Diabetes Mellitus Patients2025 · 1 citations
  5. 5Differential Effects of Aerobic, Resistance, and Combined Trainings on First‐ and Second‐Phase Insulin Secretion and Glucose Effectiveness in Type 2 Diabetes: A Randomized Controlled Trial2025 · 2 citations