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September 10, 2025Discover OncologyOpen Access

Identification of hub genes for psoriasis and thyroid cancer using bioinformatics analysis

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Authors

HSHuirong ShiYGYuan GuoJCJ. Chen

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Overview

Bioinformatics analysis uncovers differentially expressed genes in psoriasis and thyroid cancer, suggesting shared molecular pathways.

Key Points

  • A total of 79 differentially expressed genes were identified related to thyroid cancer and psoriasis.
  • Six hub genes, including SERPINA1 and CCL20, were found to have diagnostic value for both diseases.
  • Bioinformatics methods included protein-protein interaction networks and pathway enrichment analyses.
  • This research highlights potential biomarkers and therapeutic targets for thyroid cancer and psoriasis.

Cite This Study

Shi et al. (2025) studied this question.

synapsesocial.com/papers/68c23fc3b210217d64797ef7https://doi.org/10.1007/s12672-025-03305-5
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Also Consider

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  1. 1Exploring shared biomarkers and their mechanisms in thyroid cancer and systemic lupus erythematosus via bioinformatics analysis2026
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  3. 3Chemotaxis-related molecular markers underlying the immune disorder of psoriasis and ulcerative colitis: Preliminary analysis and verification2025
  4. 4Dysregulation of the cAMP Signaling Pathway Mediated by Shared Hub Genes: Diagnostic, Prognostic, and Therapeutic Insights into Thyroid Cancer and Graves' Disease2025
  5. 5Shared Molecular Mechanisms Between Type 2 Diabetes and Thyroid Cancer: Integrated Bioinformatics Insights for Prognostic Biomarker Discovery2025 · 1 citations