Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 23, 2025Scientific ReportsOpen Access

Bioinformatics analyses of comorbid mechanisms between psoriasis and type 2 diabetes mellitus

View Full Paper
Ask AI
Bookmark
Share

Authors

ZWZhimin WangJMJing Long MuYZYiwen Zhang

Discussion

Loading...

Member takes

Overview

Bioinformatics reveals altered cytokine receptor interactions and common pathophysiology in psoriasis and T2DM.

Key Points

  • Significant co-DEGs identified link psoriasis and type 2 diabetes mellitus, indicating shared pathophysiology.
  • Gene Set Enrichment Analysis showed critical pathways involving cytokine receptor interactions in both diseases.
  • Observational analysis across microarray expression profiles from Gene Expression Omnibus and various datasets facilitated discovery.
  • Findings highlight the role of immune cell infiltration in the pathogenesis of skin and metabolic diseases.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68fa32a40df2e6cd2f742156https://doi.org/10.1038/s41598-025-20762-8
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A comprehensive bioinformatics analysis of pathways and biomarkers shared between type 2 diabetes mellitus and chronic obstructive pulmonary disease2025 · 1 citations
  2. 2Identification of hub genes for psoriasis and thyroid cancer using bioinformatics analysis2025 · 1 citations
  3. 3Chemotaxis-related molecular markers underlying the immune disorder of psoriasis and ulcerative colitis: Preliminary analysis and verification2025
  4. 4Identification and analysis of key genes and signaling pathways associated with Type 1 diabetes mellitus by bioinformatics analysis of next generation sequencing data2025 · 1 citations
  5. 5Identification of key interactive genes and their potential biological functions in type 2 diabetes and Sjögren’s syndrome2025