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September 10, 2025Journal of Stem Cell Research and Tissue EngineeringOpen Access

Long-Term Evaluation of the Safety and Effectiveness of Neural Stem Cell Transplantation for Chronic Thoracic Spinal Cord Injury

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Authors

HMHanisa Aulia MaharaniHHarmin

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Overview

Literature review shows neural stem cells improve function in chronic thoracic spinal cord injury, suggesting multimodal approaches may enhance treatment outcomes.

Key Points

  • Neural stem cell transplantation may improve motor function and reduce spasticity in chronic spinal cord injury patients.
  • Studies reveal fetal-derived neural stem cells exhibit a strong safety profile, with minimal tumor formation risk.
  • The inflammatory environment post-injury challenges the success of neural stem cell therapies, necessitating immunosuppressive regimens.
  • Long-term recovery after spinal cord injury requires addressing both neural regeneration and immune modulation.

Cite This Study

Maharani et al. (2025) studied this question.

synapsesocial.com/papers/68c23f1fb210217d64795822https://doi.org/10.20473/jscrte.v9i1.73556
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stem Cell Therapy for Spinal Cord Injury2025
  2. 2Advancements in Spinal Cord Injury Treatment: Integrating Drug Delivery, Biophysical Stimulation, Cell-Based Therapies, and Tissue Engineering Approaches2025 · 7 citations
  3. 3Exploring the Emerging Role of Stem Cell Therapy in Neurodegenerative Diseases and Spinal Cord Injury: A Narrative Review2025 · 2 citations
  4. 4<b>Tissue-Engineered Neural Stem Cell Scaffolds in Spinal Cord Injury: Insights into Materials, Molecular Pathways, and Regenerative Applications</b>2025
  5. 5Adipocyte-Derived Stem Cells in the Treatment of Spinal Cord Injuries in Animal Models: A Systematic Review2025