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August 16, 2025CureusOpen Access

Exploring the Emerging Role of Stem Cell Therapy in Neurodegenerative Diseases and Spinal Cord Injury: A Narrative Review

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Authors

AKAnvvi KademaniCAConstantinos AvraamDMDaniel Montenegro

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Overview

Narrative review highlights stem cell therapy's potential for neurodegenerative diseases and spinal cord injury, suggesting new treatment avenues.

Key Points

  • Stem cell therapy shows promise in treating neurodegenerative diseases and spinal cord injury, yet outcomes remain variable and debated.
  • Recent developments in stem cell therapy, including genetic modifications and biomaterials, aim to enhance treatment efficacy.
  • Observational analysis addressing the role of stem cells, neuroprotective mechanisms, and challenges like graft vs. host reaction is crucial.
  • Significant ethical concerns and regulatory frameworks are needed to ensure safe clinical application of stem cell therapy.

Cite This Study

Kademani et al. (2025) studied this question.

synapsesocial.com/papers/68c235fdb210217d64772df8https://doi.org/10.7759/cureus.89629
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stem Cell Therapy for Spinal Cord Injury2025
  2. 2THE USE OF STEM CELLS IN THE TREATMENT OF NEURODEGENERATIVE DISEASES - CURRENT STATE OF RESEARCH AND CLINICAL PERSPECTIVES2025
  3. 3Stem cells therapy in neurodegenerative and neuroimmune diseases: current status of treatments and future prospects2025 · 11 citations
  4. 4Current frontiers in spinal cord injury research: A narrative review2025 · 6 citations
  5. 5Advancements in Spinal Cord Injury Treatment: Integrating Drug Delivery, Biophysical Stimulation, Cell-Based Therapies, and Tissue Engineering Approaches2025 · 9 citations