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August 4, 2025ACS Applied Bio Materials

Advancements in Spinal Cord Injury Treatment: Integrating Drug Delivery, Biophysical Stimulation, Cell-Based Therapies, and Tissue Engineering Approaches

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Authors

MBManini BhattBDBodhisatwa Das

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Overview

Review discusses drug delivery, cell-based therapies, and biophysical stimulation in spinal cord injury recovery, highlighting their combined potential.

Key Points

  • Current spinal cord injury treatments include surgery and physiotherapy, but they often yield only temporary relief.
  • Cell-based therapies like stem cells show promise for improving axonal regrowth and reducing inflammation.
  • Biophysical stimulation methods aim to enhance neural plasticity and aid in functional recovery.
  • Combining biomaterials with cell-based systems and drug delivery strategies could lead to significant advances in recovery efforts.

Cite This Study

Bhatt et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d08d8https://doi.org/10.1021/acsabm.5c00459
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Current frontiers in spinal cord injury research: A narrative review2025 · 6 citations
  2. 2Repairing spinal cord injuries: the most promising current 1 biomaterials 2 for scaffolding and drug delivery, and the need for upgrade2025
  3. 3Stem Cell Therapy for Spinal Cord Injury2025
  4. 4The Interplay Between Neuromodulation and Stem Cell Therapy for Sensory-Motor Neuroplasticity After Spinal Cord Injury: A Perspective View2026 · 1 citations
  5. 5Cellular and Molecular Approaches to Spinal Cord Repair: A Hypothetical Therapeutic Framework2025