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September 10, 2025International Journal of BiomedicineOpen Access

Synergistic Effects of Amino Acid Combination in Streptozotocin-Induced Diabetic Rats: Amelioration of Hyperglycemia, Hematological Aberrations, and Pancreatic Damage

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Overview

Experimental analysis reveals that amino acid combination reduces hyperglycemia and promotes pancreatic regeneration in diabetic rats, suggesting potential therapeutic benefits.

Key Points

  • AAC treatment significantly reduced fasting blood glucose levels in STZ-induced diabetic rats, improving overall health.
  • Key metrics showed improved hematological parameters, including increases in red and white blood cell counts after AAC treatment.
  • Histopathological analysis indicated AAC partially restored pancreatic tissue structure, affecting the size and number of islets of Langerhans.
  • The findings suggest AAC has therapeutic potential for managing complications associated with type 1 diabetes mellitus.

Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/68c23d81b210217d6478de3chttps://doi.org/10.21103/article15(3)_oa20
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  1. 1Mitochondria-targeting compounds for management of metabolic and hemostatic abnormalities associated with heart dysfunctions in experimental type 2 diabetes2025
  2. 2Synergistic Effect of Combined Leaf Extract of Vernonia amygdalina, Ocimum gratissimum, and Zingiber officinale Tuber on Phytochemical Profile, Antioxidant Activity, Serum Insulin, and Biochemical Parameters in Streptozotocin-Induced Diabetic Rats2025
  3. 3RENOPROTECTIVE AND HEPATOPROTECTECTIVE POTENTIALS OF L-ARGININE AND GLUTAMATE ON STREPTOZOTOCIN INDUCED DIABETIC ALBINO RATS.2025
  4. 4ANTI-HYPERGLYCAEMIC, ANTI-LIPIDAEMIC AND ANTI-FLAMMATORY POTENTIAL OF L-ARGININE AND GLUTAMATE ON STREPTOZOTOCIN INDUCED DIABETIC ALBINO RATS.2025
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