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September 10, 2025Oncology and Translational MedicineOpen Access

Regulation of gene expression by FOXA1

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Authors

CLChenguang LiDGDawei GengWZWei Zhao

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Overview

This review explores FOXA1's role as a transcription factor in gene expression and its implications in diseases.

Key Points

  • FOXA1 plays a pivotal role in gene expression regulation, facilitating chromatin accessibility for other factors.
  • Studies indicate FOXA1's involvement in embryonic development and maintaining adult organ function.
  • Research highlights the complex interactions of FOXA1 with histone modifications affecting gene regulation.
  • Understanding FOXA1's mechanisms may reveal therapeutic targets for diseases it influences.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68c23b8fb210217d64785bd2https://doi.org/10.1097/ot9.0000000000000113
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Investigating the role of FOX gene family in development and stress response in Labeo rohita: A multi-faceted analysis of phylogeny and genome characterization2025
  2. 2Pioneer factor FOXA1 can boost CHO cell productivity2025
  3. 3DNA-binding-independent mechanisms of metabolic regulation by the Drosophila FOXO transcription factor2025
  4. 4Foxg1 and companions: Not only transcription factors2025
  5. 5The role of FoxO3a in the pathogenesis of osteoarthritis and its therapeutic applications2025