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August 21, 2025PLoS ONEOpen Access

Investigating the role of FOX gene family in development and stress response in Labeo rohita: A multi-faceted analysis of phylogeny and genome characterization

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Authors

SNSaima NazUIUrwah IshaqueACAhmad Manan Mustafa Chatha

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Overview

Computational analysis identifies 21 FOX genes in Labeo rohita, suggesting critical roles in development and stress response.

Key Points

  • The study identifies 21 FOX genes in labeo rohita, highlighting their potential role in muscle development and immune response.
  • Phylogenetic analysis grouped FOX homologs into 11 clades with other vertebrates, indicating evolutionary relationships.
  • All FOX proteins appear unstable and hydrophobic, with distinct physicochemical properties observed during analysis.
  • This research fills a significant gap in knowledge, providing a foundation for future studies in aquaculture and evolutionary biology.

Cite This Study

Naz et al. (2025) studied this question.

synapsesocial.com/papers/68af6d8a7567bf4f94feaceehttps://doi.org/10.1371/journal.pone.0323740
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Also Consider

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  1. 1Regulation of gene expression by FOXA12025
  2. 2DNA-binding-independent mechanisms of metabolic regulation by the Drosophila FOXO transcription factor2025
  3. 3The Transcriptional Regulator FOXR1 Is Required for Normal Early Embryogenesis but Dispensable for Male Fertility in Mice2025
  4. 4Gene model for the ortholog of <i>foxo</i> in <i>Drosophila sechellia</i>2025
  5. 5Predicting FOX Genes and Design of a Minimal FOX Gene Complement with a Data-Centric Machine Learning Approach2025