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September 5, 2025Food Science & NutritionOpen Access

Phytochemical Screening and Antidiabetic Potential of Paeonia emodi in Alloxan‐Induced Diabetic Rats: Investigative Study Toward Possible Mechanism

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Authors

JFJiubo FanMIMohammad IbrarMKMir Azam Khan

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Overview

Investigative study reveals Paeonia emodi's antidiabetic and hepatoprotective potential, indicating beneficial effects on blood sugar levels.

Key Points

  • Paeonia emodi extract significantly reduced fasting blood glucose levels in diabetic rats by day 21.
  • The Pe.Bt fraction showed strong inhibitory activity against α‐glucosidase, with an IC50 value of 626 μg/mL.
  • In vivo studies demonstrated that Pe.Bt (500 mg/kg) improved liver and pancreas health, protecting against alloxan-induced damage.
  • Paeonia emodi exhibited antioxidant properties, reducing levels of liver enzymes while enhancing protein levels in treated rats.

Cite This Study

Fan et al. (2025) studied this question.

synapsesocial.com/papers/68c23a2cb210217d6477f74dhttps://doi.org/10.1002/fsn3.70870
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Also Consider

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