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September 10, 2025The Journal of Basic and Applied ZoologyOpen Access

Hepatic restorative potential of Portulaca oleracea ethanolic extract and/or metformin in type II diabetes mellitus model induced by high-fat diet and STZ

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Authors

NBNaglaa BahrANAmna H M NourAEAbd M. Abd El-KaderEl-Kader

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Overview

Observational analysis showed reduced oxidative stress and inflammatory markers in diabetic rats, indicating protective benefits of purslane extract.

Key Points

  • Purslane extract improved liver damage associated with diabetes, reducing inflammation and oxidative stress.
  • Diabetic rats treated with purslane and metformin exhibited significant decreases in prooxidants and inflammatory markers.
  • The treatment revealed severe liver alterations and histopathological changes in untreated diabetic rats.
  • Combining purslane extract with metformin enhanced liver protective effects in diabetic models.

Cite This Study

Bahr et al. (2025) studied this question.

synapsesocial.com/papers/68c23e94b210217d64793787https://doi.org/10.1186/s41936-025-00476-z
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