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September 17, 2025Trends in Sciences

Exploring the Therapeutic Effects of Allium chinense G. Don Extract on Pancreatic Histopathology and Apoptosis Biomarker Modulation in Diabetic Rat Models

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Authors

HFHusnarika FebrianiSISyafruddin IlyasRSRamlan Silaban

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Overview

Experimental study shows A. chinense extract improves blood glucose and pancreatic histopathology in diabetic rats, suggesting its potential as a natural therapy.

Key Points

  • The extract significantly reduced blood glucose levels and HbA1c in diabetic rats.
  • At 600 mg/kg BW, the extract improved pancreatic histopathology and antioxidant activity.
  • Phytochemical analysis confirmed the presence of flavonoids and phenolic compounds in the extract.
  • A. chinense shows potential as a natural adjuvant for diabetes management through its antioxidant and antiapoptotic effects.

Cite This Study

Febriani et al. (2024) studied this question.

synapsesocial.com/papers/68d441a6713b0b5dfea80be9https://doi.org/10.48048/tis.2025.10638
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of the Hypoglycemic Potential of the Ethanolic Bulb Extract of Allium Chinense G. Don (Sibujing) on High-Glucose Induced Hyperglycemic Swiss Albino Mice2025
  2. 2Evaluation of the Antioxidant and Antihyperglycemic Activity: A Comparative Study of Shallot (Allium ascalonicum L.) Peel and Bulb Ethanol Extracts2025 · 1 citations
  3. 3Evaluation of the Antidiabetic, Hypolipidemic and Hepatoprotective Effect of Allium sativum in Diabetic Rats2025
  4. 4Phytochemical Profiling and Dual In Vitro In Vivo Antidiabetic Assessment of Ethyl Acetate Fraction and Essential Oil From Allium ascalonicum2025 · 5 citations
  5. 5Antidiabetic and Anti-inflammatory Effects of Peperomia pellucida Leaf Extract: Modulation of Blood Glucose, IL-1β, and Pancreatic Histopathology in STZ-Induced Diabetic Rats2025 · 1 citations