Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 5, 2025In VivoOpen Access

Peripheral Blood-based NRN1 and TNFAIP3 Gene Expression as Minimally Invasive Biomarkers for Gastric Cancer

View Full Paper
Ask AI
Bookmark
Share

Authors

DQDomingos Sávio QueirozYSYeda Beatriz Louredo dos SantosLSLEONARDO CAIRES SANTOS

Discussion

Loading...

Member takes

Overview

Observational analysis identified NRN1 as a promising biomarker in gastric cancer patients, implying its potential for non-invasive monitoring.

Key Points

  • NRN1 expression levels were significantly higher in gastric cancer patients compared to controls, indicating its potential as a biomarker.
  • The study found that NRN1 could discriminate between gastric cancer patients and healthy individuals with an area under the curve of 0.72.
  • Expression of NRN1 decreased significantly after tumor resection, suggesting its role in postoperative monitoring.
  • TNFAIP3 showed no significant difference between cancer patients and controls, highlighting the specificity of NRN1 as a biomarker.

Cite This Study

Queiroz et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d6477915bhttps://doi.org/10.21873/invivo.14065
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic value of lnc-RNAs TINCR, GC1 and AFAP1-AS1 in gastric cancer differentiation from healthy people2025
  2. 2Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer2025
  3. 3Role of NR1D1 in Colorectal Cancer: Impact on Prognosis, Immune Microenvironment, and Oncogenic Pathways2025
  4. 4Identification of tumor associated neutrophils-related genes in triple-negative breast cancer for predicting prognosis and therapeutic response through integrated single-cell analysis2025
  5. 5Spatial gene expression profiling identifies prognostic features of residual tumors after neoadjuvant chemotherapy in triple-negative breast cancer2025