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August 7, 2025Biomarkers in Medicine

Diagnostic value of lnc-RNAs TINCR, GC1 and AFAP1-AS1 in gastric cancer differentiation from healthy people

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Authors

PPPouneh PourfarzamMKMohammad Bagher Khadem‐ErfanRSRamin Shakeri

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Overview

Retrospective analysis reveals lncRNAs identify gastric cancer with notable specificity and sensitivity.

Key Points

  • Core finding shows specific lncRNAs have potential as biomarkers for diagnosing gastric cancer.
  • Significant changes in CEA and CA19.9 levels were found in patients compared to healthy controls.
  • Study involved 256 participants, with diagnostic assessment through ROC curve analysis of lncRNAs.
  • Identifying dysregulated lncRNAs can improve noninvasive diagnostic methods for gastric cancer.

Cite This Study

Pourfarzam et al. (2025) studied this question.

synapsesocial.com/papers/689521f09f4f1c896c42879ehttps://doi.org/10.1080/17520363.2025.2542112
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Also Consider

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  1. 1Competing Endogenous RNA Networks Reveal Long Non-coding RNAs as Potential Prognostic Biomarkers in Gastric Cancer: A Systematic Review and Meta-Analysis2025
  2. 2Identification of lncRNA <i>HCCAT5</i> as a Novel Biomarker for Gastric Cancer2025
  3. 3Long Intergenic Non-coding RNA — LINC00659 — Expression Changes in Gastric Cancer: Lessons from Northwestern Iran2025
  4. 4Peripheral Blood-based <i>NRN1</i> and <i>TNFAIP3</i> Gene Expression as Minimally Invasive Biomarkers for Gastric Cancer2025
  5. 5The Role of the TIMP1/LINC01615 Axis as a Regulator of the EMT Pathway in Gastric Cancer2025 · 3 citations