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September 5, 2025International Journal of Biology and Life SciencesOpen Access

Study on the Mechanism of the Buqi Tongqiao Formula in Regulating the PI3K/AKT/mTOR Pathway to Intervene in IgA Nephropathy in Rats

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Authors

JXJinjiang XuMZMan ZhangQWQiuye Wu

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Overview

Observational analysis shows BQTQF improves renal function in IgAN, highlighting its potential therapeutic role.

Key Points

  • BQTQF significantly improved renal function in IgAN rats, reducing levels of 24-hour urinary protein and Scr.
  • After treatment, mRNA levels of PI3K, AKT, and mTOR were decreased, suggesting BQTQF's regulatory effect.
  • The study utilized rats with an IgAN model, demonstrating the potential mechanism of action for BQTQF.
  • BQTQF alleviates renal pathological damage, indicating its therapeutic potential in managing IgA nephropathy.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68c2384fb210217d6477763fhttps://doi.org/10.54097/4kk71643
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