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September 10, 2025Medical science monitor basic research/Medical science monitor. Basic researchOpen Access

Therapeutic Mechanisms of Jinshuiqing in IgA Nephropathy: A Transcriptomic Analysis

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Authors

ZZZhijian ZhaWSWenzhu SongRWRui Wang

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Overview

Transcriptomic analysis reveals that Jinshuiqing modifies gene expression and improves kidney function in IgAN, suggesting therapeutic potential.

Key Points

  • Jinshuiqing treatment significantly modulates gene expression in IgAN mice, enhancing kidney function and regulating immune responses.
  • Differential analysis identified 118 genes with considerable changes, indicating that Jinshuiqing affects inflammation and metabolic pathways.
  • Transcriptomic and pathway enrichment analyses suggest that Jinshuiqing alleviates oxidative stress in IgA nephropathy.
  • Findings highlight the therapeutic efficacy of Jinshuiqing for improving overall kidney health in IgAN patients.

Cite This Study

Zha et al. (2025) studied this question.

synapsesocial.com/papers/68c23a74b210217d64780e6dhttps://doi.org/10.12659/msmbr.950343
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