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August 19, 2025Frontiers in PsychiatryOpen Access

Effect of nonpharmacologic therapies on depressive symptoms in patients with chronic fatigue syndrome: a network meta-analysis

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Authors

BJBo JiangMCMengru CaoXXXia Xue

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Overview

Network meta-analysis shows diet therapy significantly reduces depressive symptoms in chronic fatigue syndrome patients, implying its potential effectiveness.

Key Points

  • Diet therapy most effectively reduced depressive symptoms in chronic fatigue syndrome patients, resulting in substantial improvements over control measures.
  • Analysis revealed that diet therapy had a standard mean difference of -5.64, indicating strong efficacy compared to other interventions.
  • Randomized controlled trials were reviewed through a network meta-analysis conducted across multiple databases until March 2025.
  • Implications suggest that nonpharmacologic therapies, especially diet, may offer critical support in managing depression in chronic fatigue syndrome patients.

Cite This Study

Jiang et al. (2025) studied this question.

synapsesocial.com/papers/68c237aeb210217d64776628https://doi.org/10.3389/fpsyt.2025.1657615
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