Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 25, 2025Open Access

Effectiveness of non-pharmacological Interventions For Fatigue in Long term conditions (EIFFEL) - systematic review and network meta-analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

JLJoanna LeavissCBChristopher Burton

Discussion

Loading...

Member takes

Overview

Systematic review shows cognitive behavioural therapy and physical activity reduce fatigue in long term conditions, indicating their effectiveness in management.

Key Points

  • Non-pharmacological interventions can effectively reduce fatigue in adults with long-term medical conditions.
  • Cognitive behavioural therapy showed a substantial reduction in fatigue at both end of treatment and long-term follow-up.
  • Physical activity promotion significantly decreased fatigue across various time points and conditions.
  • Evidence strength for non-pharmacological methods is moderate to low, with limited studies outside multiple sclerosis.

Cite This Study

Leaviss et al. (2025) studied this question.

synapsesocial.com/papers/689a0933e6551bb0af8ce2e6https://doi.org/10.1101/2025.07.23.25332061
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Economic evaluation of non-pharmacological interventions for fatigue in patients with long-term medical conditions2025
  2. 2Cost effectiveness of non-pharmacological interventions for fatigue in patients with long-term conditions: a systematic literature review2025
  3. 3A scoping review of non-pharmacological interventions for managing fatigue across the lifespan of people living with musculoskeletal (MSK) conditions2025
  4. 4Effect of nonpharmacologic therapies on depressive symptoms in patients with chronic fatigue syndrome: a network meta-analysis2025
  5. 5Application of telemedicine in fatigue management for patients with multiple sclerosis: A scoping review2025