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August 17, 2025Al-Kufa University Journal for BiologyOpen Access

Genotypic and Phenotypic Detection of Carbapenemase Genes in Clinical and Environmental Isolates of Klebsiella pneumoniae ST23

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Authors

SMS A MohammedAAAli Shakir Obeed Al-MamooriHMHuda Mohammed

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Overview

This analysis reveals high prevalence and antimicrobial resistance of K. pneumoniae ST23 in clinical samples, indicating heightened infection risks in hospitals.

Key Points

  • Of 150 samples, 43 (28.6%) were identified as carbapenemase-producing K. pneumoniae ST23, pointing to significant health risks.
  • Most resistant isolates (60.5%) derived from clinical specimens, especially urine and wound swabs, suggesting high hospital exposure.
  • Multiplex PCR detected multiple carbapenemase genes, with bla_NDM found in 58.1% of the isolates, indicating complex resistance patterns.
  • These findings highlight the urgent need for improved hygiene and surveillance to prevent hospital-acquired infections caused by resistant bacteria.

Cite This Study

Mohammed et al. (2025) studied this question.

synapsesocial.com/papers/68c23652b210217d64773ec4https://doi.org/10.36320/ajb/v17.i2.20185
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Also Consider

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  1. 1Emergence and molecular evolution of carbapenem-resistant hypervirulent ST23 Klebsiella pneumoniae : The superbug phenomenon in China2025 · 14 citations
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  3. 3Global Epidemiology and Antimicrobial Resistance of Klebsiella Pneumoniae Carbapenemase (KPC)-Producing Gram-Negative Clinical Isolates: A Review2025 · 37 citations
  4. 4The Molecular Characteristics of Extended-Spectrum β-Lactamases (ESBL), Carbapenem-Resistant Enterobacterales (CRE) and Susceptible Isolates of Klebsiella pneumoniae and Escherichia coli in Hospital Pakar Universiti Sains Malaysia (HPUSM), Kelantan2025
  5. 5Carbapenemase-encoding genes in critical gram-negative bacteria isolated from ICU patients with infections and/or gastrointestinal carriage, and environmental samples in the amhara National Regional state, Ethiopia2025