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August 15, 2025VirulenceOpen Access

Emergence and molecular evolution of carbapenem-resistant hypervirulent ST23 Klebsiella pneumoniae : The superbug phenomenon in China

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Authors

TCTao ChenXWXueting WangLXLuying Xiong

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Overview

Epidemiological analysis reveals geographic hotspots for ST23 CR-hvKP in China, suggesting urgent surveillance is needed.

Key Points

  • The emergence of ST23 carbapenem-resistant hypervirulent Klebsiella pneumoniae reflects growing public health concerns.
  • Epidemiological data show hotspots in Hebei and Jiangxi, with specific carbapenem resistance genes dominating different regions.
  • Comprehensive analysis based on 30 studies outlines geography and transmission patterns for this superbug phenomenon.
  • Highlighting the need for enhanced tracking efforts to prevent further spread and resistance escalation in clinical settings.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c235ccb210217d64771fc8https://doi.org/10.1080/21505594.2025.2545556
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Genotypic and Phenotypic Detection of Carbapenemase Genes in Clinical and Environmental Isolates of Klebsiella pneumoniae ST232025
  2. 2Geographic containment and virulence‐resistance trade‐offs drive the evolution of hypervirulent <i>Klebsiella pneumoniae</i>2025
  3. 3Hv-CRKP: Unraveling the Global Epidemiological Landscape and Divergence in Genetic Evolutionary Mechanisms2026
  4. 4Molecular characterization of colistin resistance in carbapenem-resistant <i>Klebsiella pneumoniae</i> from a tertiary hospital in China2025 · 3 citations
  5. 5Molecular and virulence differences of Klebsiella pneumoniae isolated from blood2025 · 1 citations