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August 12, 2025Infection and ChemotherapyOpen Access

Genetic Epidemiology and Antimicrobial Susceptibilities of Carbapenem-Resistant Pseudomonas aeruginosa Isolates from a Multicenter Study in Korea

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Authors

TKTark KimYHYoon-Kyoung HongSPSeonghee Park

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Overview

Investigation reveals high prevalence of carbapenemase in Pseudomonas aeruginosa isolates, suggesting urgent need for effective treatments.

Key Points

  • 73% of carbapenem-resistant pseudomonas aeruginosa isolates carried carbapenemase genes, highlighting a significant resistance issue.
  • The most common genotype was blaNDM ST773, found in 27 isolates, indicating genetic diversity among the strains.
  • Susceptibility to ceftazidime/avibactam was only 17.5%, with none of the carbapenemase-producing isolates responding effectively.
  • Ongoing monitoring is crucial, as increased resistance patterns may complicate treatment options in clinical settings.

Cite This Study

Kim et al. (2025) studied this question.

synapsesocial.com/papers/68c23595b210217d64771331https://doi.org/10.3947/ic.2025.0032
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antimicrobial Resistance Mechanisms in Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> Clinical Strains Isolated in Shanghai, China2025
  2. 2Molecular insights into the persistence and co-occurrence of two different carbapenem-resistant <i>Pseudomonas aeruginosa</i> lineages within a hospital setting2025
  3. 3Bla producing Pseudomonas aeruginosa ST235 is involved in resistance to different β-lactams2025
  4. 4Molecular Epidemiology of Infections Caused by Carbapenem-Resistant &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; and Enterobacterales and Susceptibility of Isolates to Ceftazidime-Avibactam2025
  5. 5Carbapenem Resistance among &lt;i&gt;Pseudomonas aeruginosa&lt;/i&gt; isolated from Clinical Samples with a Special Reference to Colistin Resistance2025