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November 27, 2023Pakistan Journal of Medical & Health Sciences

Efficacy of Antibiotic Prophlaxis in Preventing Surgical Site Infections: A Review of Current Practices and Emerging Alternatives in General and Plastic Surgery

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Authors

AAAsghar AliJKJaved KhanHAHafiz Waqas Ahmed

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Overview

Prospective analysis reveals antibiotic prophylaxis significantly reduces SSI rates in general and plastic surgery, suggesting improvements in infection control practices.

Key Points

  • Cefazolin proved to be the most effective antibiotic for reducing surgical site infections, with an incidence of 14.66%.
  • Patients undergoing general surgery showed higher infection rates compared to those in plastic surgery, although not statistically significant.
  • A prospective observational study monitored 116 surgical patients for 30 days post-operation, evaluating antibiotic regimens and infection rates.
  • Wound classification and use of drains were significantly linked to infection risk, highlighting critical areas for optimizing infection control.

Cite This Study

Ali et al. (2023) studied this question.

synapsesocial.com/papers/68af80717567bf4f94ff71d1https://doi.org/10.53350/pjmhs020231711146
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of the timing of antibiotic prophylaxis on the surgical site infections in patients undergoing elective general surgery2025 · 1 citations
  2. 2A comparative study of surgical site infections in clean elective surgical procedures with and without antibiotic prophylaxis2025
  3. 3Optimizing Surgical Prophylaxis: An Audit of Antibiotic Use and Guideline Adherence in a Tertiary Care Hospital with Focus on Antimicrobial Stewardship2025
  4. 4Use of Antibiotic Prophylaxis for Surgical Site Infection Prevention in Nononcologic Breast Surgery: A Scoping Review2025
  5. 5Association between prophylactic antibiotics and surgical site infections in bimaxillary orthognathic surgery: a retrospective study2025