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September 10, 2025Annals of Plastic Surgery

Use of Antibiotic Prophylaxis for Surgical Site Infection Prevention in Nononcologic Breast Surgery: A Scoping Review

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Authors

EAErin AbbottBLBrittany G. LivelyAJAndrew James

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Overview

Scoping review analyzes antibiotic prophylaxis impact on surgical site infection in breast surgeries, suggesting variable efficacy across procedures.

Key Points

  • Antibiotic prophylaxis may reduce surgical site infection in breast reduction surgeries, but evidence is mixed for other procedures.
  • Randomized controlled trials reported significant reductions in surgical site infection during risk-reducing mastectomy with antibiotics, yet mixed outcomes overall.
  • Findings from systematic reviews and clinical trials indicate that the effectiveness of antibiotic prophylaxis is highly dependent on the surgical procedure type.
  • The role of antibiotic prophylaxis in nononcologic breast surgery remains unclear, highlighting the need for further high-quality clinical trials.

Cite This Study

Abbott et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d6478aed2https://doi.org/10.1097/sap.0000000000004474
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Is Antibiotic Prophylaxis Necessary in Mastectomy with Antimicrobial Sutures? A Comparative Analysis2025
  2. 2Efficacy of Antibiotic Prophlaxis in Preventing Surgical Site Infections: A Review of Current Practices and Emerging Alternatives in General and Plastic Surgery2023
  3. 3A comparative study of surgical site infections in clean elective surgical procedures with and without antibiotic prophylaxis2025
  4. 4“Single-dose versus 24-hour antibiotic prophylaxis in reduction mammaplasty: a randomized controlled trial”2025
  5. 5The impact of antibiotic prophylaxis on postoperative infections in breast cancer surgery – a retrospective quality assessment2025