Seeding of visceral adipose tissue with perinatally generated regulatory T cells shapes the metabolic tenor in mice

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Research reveals perinatal regulatory T cells shape visceral adipose tissue and insulin resistance in mice, indicating immune system complexity.

Perinatal regulatory T cells influence the metabolic environment in visceral adipose tissue, contributing to metabolic health.
Mice on a high-fat diet showed profound insulin resistance linked to changes in their visceral adipose tissue Treg compartment.
Analysis conducted on mice with differing dietary regimens illustrates the role of perinatal Tregs in immune system function.
These findings highlight the importance of early immune development on long-term metabolic outcomes, suggesting new therapeutic directions.

Marin-Rodero et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Research reveals perinatal regulatory T cells shape visceral adipose tissue and insulin resistance in mice, indicating immune system complexity.