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August 21, 2025EndocrinesOpen Access

Developmental Origin and Functional Diversity of Foxp3+ Regulatory T Cells in Diabetes and Obesity

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Authors

AYAçelya YilmazerDZDimitra Maria ZevlaKKKarsten Kretschmer

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Overview

Review explores Treg cell roles in metabolic regulation and autoimmunity in diabetes, suggesting new therapeutic directions.

Key Points

  • Dysfunction of foxp3+ treg cells is implicated in the development of both type 1 and type 2 diabetes.
  • Treg cells play crucial roles in modulating inflammation and supporting repair processes in metabolic organs.
  • The review emphasizes the importance of both thymic and peripheral treg cells in immune dysregulation related to metabolic diseases.
  • Targeting specific treg cell subsets could provide new therapeutic strategies to prevent or slow disease progression.

Cite This Study

Yilmazer et al. (2025) studied this question.

synapsesocial.com/papers/68af6d967567bf4f94feb2a2https://doi.org/10.3390/endocrines6030041
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