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August 25, 2025Bioscientia Medicina Journal of Biomedicine and Translational ResearchOpen Access

The Emerging Role of Integrins in Diabetic Kidney Disease: A Systematic Review and Meta-Analysis of Their Diagnostic and Prognostic Utility for Early Risk Stratification

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Authors

MAMazaya Indah Brillian AmadeaDPDrajad Priyono

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Overview

Systematic review identifies integrins' utility for early diagnosis and risk stratification in diabetic kidney disease.

Key Points

  • Integrins show significant promise as biomarkers for early diabetic kidney disease detection.
  • The pooled sensitivity for early diagnosis of diabetic kidney disease was 0.88, and specificity was 0.85.
  • This systematic review utilized bivariate random-effects models and pooled data from eight studies with 2,874 patients.
  • Findings may guide future studies on the clinical relevance of non-invasive integrin measurements.

Cite This Study

Amadea et al. (2025) studied this question.

synapsesocial.com/papers/68af7b187567bf4f94ff29a2https://doi.org/10.37275/bsm.v9i11.1430
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Also Consider

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  1. 1Assessment and prediction of diabetic kidney disease in patients with type 2 diabetes mellitus by using an advanced biomarkers2025
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  4. 4The longitudinal associations of selected Tubular Biomarkers Predict the Risk of Nephropathy Progression in Diabetic Patients: systematic review and meta-analysis2025 · 1 citations
  5. 5Novel Management Approaches Diabetic Kidney Disease and Chronic Kidney Disease: A Systematic Review2025