Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 14, 2025PharmaceuticalsOpen Access

Eugenia uniflora L.: Analysis of Chemical Profile and Cytotoxic Action on Tumor (HeLa) and Non-Tumor Cells (NIH/3T3)

View Full Paper
Ask AI
Bookmark
Share

Authors

LPLetícia M. R. PescinelliMLMilena França LongueGOGuilherme Oliveira

Discussion

Loading...

Member takes

Overview

Analysis reveals cytotoxicity and potential metabolic modulation in HeLa and NIH/3T3 cells, suggesting therapeutic avenues.

Key Points

  • EUD and EUA extracts showed significant cytotoxicity against HeLa cells, leading to potential cancer treatment options.
  • The IC50 values for the extracts were 63.03 μg/mL for EUH, 33.79 μg/mL for EUD, and 38.38 μg/mL for EUA.
  • Using methods like MTT assays and LC-MS/MS, flavonoids and phenolic compounds were identified in the extracts.
  • These findings indicate that EUD and EUA can inhibit cervical cancer cell migration and affect the cell cycle.

Cite This Study

Pescinelli et al. (2025) studied this question.

synapsesocial.com/papers/68af70757567bf4f94fec3a9https://doi.org/10.3390/ph18081199
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1In Vitro and In Silico Evaluation of the Anti-Aging Potential of Eugenia uniflora UAE Extracts2025 · 2 citations
  2. 2Comparative evaluation of the allelopathic interference of inside and peripheral extracts of <i>Eugenia florida</i> DC leaves on the primary development, mitotic index and chromosomal abnormalities of <i>Lactuca sativa</i> L2025
  3. 3Effect of ultrasonic-assisted extraction (UAE) method extraction time on the cytotoxic activity of young bay leaf extract (Eugenia polyantha Wight) on T47D breast cancer cells and determination of flavonoid levels2025
  4. 4Species of the Genus <i>Eugenia</i>: Bioactive Effects and Toxicity2025
  5. 5Study on Antitumor Secondary Metabolites from <i>Euphorbia ebracteolata</i> Hayata: Structural Characterization, Network Pharmacology, Molecular Docking and <i>In Vitro</i>2025 · 1 citations