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July 31, 2025PharmacianaOpen Access

Effect of ultrasonic-assisted extraction (UAE) method extraction time on the cytotoxic activity of young bay leaf extract (Eugenia polyantha Wight) on T47D breast cancer cells and determination of flavonoid levels

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Authors

RSRiisyda Faila SufaDHDevi Nisa Hidayati

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Overview

This observational analysis shows varying extraction times impact flavonoid levels and cytotoxic activity in T47D breast cancer cells, suggesting effective natural anticancer properties.

Key Points

  • Young bay leaf extract demonstrated varying cytotoxic activity with IC50 values between 735μg/mL and 1007μg/mL.
  • Total flavonoid content of the extract increased with longer ultrasonic-assisted extraction times, reaching up to 2.61mgQE/g.
  • Cytotoxic activity was measured using the MTT assay method, highlighting the extract's potential against T47D breast cancer cells.
  • Study results suggest that ultrasonic-assisted extraction effectively enhances the extraction efficiency of flavonoids from Eugenia polyantha.

Cite This Study

Sufa et al. (2025) studied this question.

synapsesocial.com/papers/68af2d76cf1dd9ea359e55e7https://doi.org/10.12928/pharmaciana.v15i2.29279
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