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August 20, 2025Open Access

Prevalence and risk factors of fluoroquinolone resistance in Gram-negative bacterial infections: a systematic review and meta-analysis

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Authors

MAMade Bayu AnggriawanIRIke Dhiah Rochmawati

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Overview

Systematic review reports 35% prevalence of fluoroquinolone resistance in Gram-negative bacteria, highlighting key risk factors.

Key Points

  • Pooled prevalence of fluoroquinolone resistance was 35%, indicating a significant public health concern requiring attention.
  • Key risk factors for fluoroquinolone resistance include prior antibiotic use and indwelling catheter presence.
  • Systematic review analyzed 24 studies published between 2014 and 2024 across various databases.
  • Understanding these factors may improve clinical decision-making for managing antibiotic resistance.

Cite This Study

Anggriawan et al. (2025) studied this question.

synapsesocial.com/papers/68af409acf1dd9ea359ec90chttps://doi.org/10.22541/au.175569062.26673140/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tackling the Threat: A Review of Fluoroquinolone Resistance in Salmonella and Campylobacter in Food-Producing Animals2025
  2. 2Detection of Fluoroquinolones Antibiotic Resistant in Pseudomonas Aeruginosa Isolates2025
  3. 3PATTERNS OF ANTIBIOTIC RESISTANCE IN COMMON UROPATHOGENS ISOLATED FROM PATIENTS WITH RECURRENT URINARY TRACT INFECTIONS: A SYSTEMATIC REVIEW2025
  4. 4Meta-analysis of fluoroquinolone antibiotics in the treatment of pelvic inflammatory disease and associated risk factors2025
  5. 5Should we stop using fluoroquinolone in non-tuberculosis patients? A study to assess the drug resistance profile of rifampicin-resistant pulmonary tuberculosis2025