Should we stop using fluoroquinolone in non-tuberculosis patients? A study to assess the drug resistance profile of rifampicin-resistant pulmonary tuberculosis

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Observational study reveals high fluoroquinolone resistance in RR-TB patients, suggesting impact on drug use policy.

Over half of the studied RR-TB patients had fluoroquinolone resistance, complicating treatment options.
Among 607 RR-TB patients, 477 (78.5%) were resistant to isoniazid, highlighting multiple drug resistance.
The analysis involved using line probe assay to detect resistance types, providing critical resistance data.
Findings may necessitate changes in fluoroquinolone usage for non-TB patients to reduce further resistance.

Shukla et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark