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August 20, 2025MedicinaOpen Access

The Effects of Hyaluronic Acid on Gait Parameters in Patients with Knee Osteoarthritis: A Systematic Literature Review

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Authors

CCCosimo CostantinoSRS. RonzoniAIAnnalisa Ingletto

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Overview

Systematic review demonstrates improved gait and pain relief in knee osteoarthritis with hyaluronic acid injections, suggesting benefits for rehabilitation.

Key Points

  • Patients treated with hyaluronic acid injections showed significant improvements in gait parameters and pain management.
  • A total of 321 patients were evaluated across 13 studies, revealing enhanced walking speed and cadence post-treatment.
  • Gait analysis combined with clinical scores like the VAS and WOMAC provided a comprehensive view of treatment effectiveness.
  • Findings indicate that hyaluronic acid injections not only relieve pain but also enhance rehabilitation outcomes post-treatment.

Cite This Study

Costantino et al. (2025) studied this question.

synapsesocial.com/papers/68af4088cf1dd9ea359ec035https://doi.org/10.3390/medicina61081488
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of corticosteroids and hyaluronic acid injections on knee osteoarthritis trajectory2025 · 4 citations
  2. 2Intra-Articular Use of Hyaluronic Acid Preparations in the Treatment of Knee Osteoarthritis2025
  3. 3Impact of intra-articular high-concentration hyaluronic acid administration on the innate immune response in experimental knee osteoarthritis2025
  4. 4Enhanced Synovial Fluid Rheology in Moderate Knee Osteoarthritis Through Combined Intra-Articular Hyaluronic Acid and Multimodal Physiotherapy: A Monocentric Observational Study2025
  5. 5Comparison of the effects of intra-articular Hyaluronic Acid Versus Methyl Prednisolone Acetate in Iraqi patients with Knee Osteoarthritis; A Double-Blind Controlled Study2025