Effect of corticosteroids and hyaluronic acid injections on knee osteoarthritis trajectory

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Discussion

Observational study compares corticosteroids and hyaluronic acid injections in knee OA patients, highlighting distinct outcomes.

Corticosteroids showed clinically relevant short-term benefits for knee OA compared to hyaluronic acid.
Both treatment groups did not experience overall worsening of knee osteoarthritis after 36 months.
Hyaluronic acid was associated with long-term functional improvement in knee OA symptoms.
No significant differences were found in joint space narrowing progression or the need for knee arthroplasty between treatments.

Bensa et al. (2025) studied this question.

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View Full Paper

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Authors

Observational study compares corticosteroids and hyaluronic acid injections in knee OA patients, highlighting distinct outcomes.

Corticosteroids showed clinically relevant short-term benefits for knee OA compared to hyaluronic acid.
Both treatment groups did not experience overall worsening of knee osteoarthritis after 36 months.
Hyaluronic acid was associated with long-term functional improvement in knee OA symptoms.
No significant differences were found in joint space narrowing progression or the need for knee arthroplasty between treatments.

Bensa et al. (2025) studied this question.

View Full Paper

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