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August 18, 2025Saudi Journal of Biomedical ResearchOpen Access

Design, Synthesis, Characterizations and Biological Evaluations of Substituted 2-((3-Chloro-2-Methylphenyl) ((1-Phenyl-1H-1,2,3-Triazol-4-Yl) Methyl) Amino) Benzoic Acid Derivatives

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Authors

LRLakavath RamdasDVDharmasoth VeerannaGRG. Ravi

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Overview

This research demonstrates antibacterial and antifungal properties in triazole derivatives, indicating potential for cancer therapy.

Key Points

  • Several derivatives exhibit significant antibacterial and antifungal activity, indicating their effectiveness against various strains.
  • Compounds showed potent cytotoxic effects against human cancer cell lines, with some outpacing standard treatments.
  • Molecular docking studies suggest that these derivatives may function as inhibitors for lipid biosynthesis in cancer therapy.
  • The use of click chemistry enabled the efficient synthesis of these novel compounds, enhancing their therapeutic potential.

Cite This Study

Ramdas et al. (2025) studied this question.

synapsesocial.com/papers/68af35efcf1dd9ea359ea805https://doi.org/10.36348/sjbr.2025.v10i08.001
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