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August 1, 2025British journal of surgery

The impact of antibiotic prophylaxis on postoperative infections in breast cancer surgery – a retrospective quality assessment

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Authors

AEAlice Ekros

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Overview

Retrospective analysis finds no significant difference in infection rates post-breast cancer surgery, implying the need for careful consideration of antibiotic use.

Key Points

  • Postoperative infection rates after breast cancer surgery were 14%, and 72% of patients received prophylactic antibiotics.
  • No significant difference was found in infection rates between those who received antibiotics and those who did not, with a p-value of 0.88.
  • The investigation incorporated a retrospective quality assessment of records from 578 patients undergoing surgery at Skåne University Hospital in 2022.
  • While surgical complexity influenced infection risk, only higher body mass index showed a significant correlation with increased infection risk (p = 0.01).

Cite This Study

Alice Ekros (2025) studied this question.

synapsesocial.com/papers/68af268acf1dd9ea359e1a5ahttps://doi.org/10.1093/bjs/znaf149.020
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Use of Antibiotic Prophylaxis for Surgical Site Infection Prevention in Nononcologic Breast Surgery: A Scoping Review2025
  2. 2Is Antibiotic Prophylaxis Necessary in Mastectomy with Antimicrobial Sutures? A Comparative Analysis2025 · 1 citations
  3. 3Major systemic infection following breast cancer surgery and oncological outcomes2025
  4. 4Major systemic infection following breast cancer surgery associated with worse oncological outcomes2025
  5. 5Risk factors for postoperative abdominal infection of colorectal cancer: A systematic review based on the PRISMA guidelines2026